THE UFABET BY LIGAZ DIARIES

DNA ligases seal 5′-PO4 and three′-OH polynucleotide ends through three nucleotidyl transfer ways involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are vital guardians of genomic integrity, and ligase dysfunction underlies human genetic ailment syndromes. Crystal constructions of DNA ligases sure to nucleotide and nucleic